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According to the Journal of Pharmacopuncture, when nicotine hits, it binds to specific receptors in your brain and triggers the release of neurotransmitters like dopamine

This is hardly a complete survey of research in the field, and as usual with academic literature the findings can be mixed due to different data sets, time periods and other methodological differences

J Pharmacol Exp Ther 2002

Below is a state-by-state synopsis of THCa legality as of this writing