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Nicotine Replacement Therapy (NRT) Although co-administration of varenicline (1 mg twice daily) and transdermal nicotine (21 mg/day) for up to 12 days did not affect nicotine pharmacokinetics, the incidence of nausea, headache, vomiting, dizziness, dyspepsia, and fatigue was greater for the combination than for NRT alone

Given your interest in VELO as a potential alternative, we understand that you are likely already aware of the significant health risks associated with traditional cigarette smoking

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[2] Snuff originated in the Americas, [3] and was commonly used in Europe by the 17th century

Biology (Basel)