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Van Duuren, B

The toxins in cigarette smoke also alter the bodys immune system by slowing the white blood cells ability to respond to infections

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It is also to be noted that genetic factors contribute

In France, increases in tobacco taxation that began in the 1990s led to a threefold increase in the inflation-adjusted price of cigarettes and, by 2005, to a halving of cigarette consumption from around six cigarettes per adult per day to three cigarettes per day

the National Institute of Allergy and Infectious Diseases of the National Institutes of Health (award number 1R21AI187857-01)