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Nicotine and Dopamine Release in the Shell of the Nucleus Accumbens In humans smoking a cigarette increases dopmaine release in the area of the nuculus accumbens in the ventral striatum and increased dopamine release significantly relates to an improvement in mood Smoking Releases Dopamine in the Ventral Striatum and Improves Mood CURRENT LESSON OBJECTIVES Describe the Sequence of Factors that leads to Smoking Addiction What is the mechanism by which nicotine produces its biological and behavioral effects

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However, taking the drug may cause dependent individuals to wake up at night for a quick smoke due to falling levels of the drug, leading to significant sleep disturbances