This extremely high and anxiogenic value got the attention of the media and has been applied everywhere since then without much thought, with an equivalence to air pollution of 1 cigarette = 22 g/m3
Oakes JM, Xu J, Morris TM et al (2020) Effects of Chronic Nicotine Inhalation on Systemic and Pulmonary Blood Pressure and Right Ventricular Remodeling in Mice
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"Smokers who viewed plain packs also thought the cigarettes would be less satisfying and enjoyable to smoke than those who viewed branded packs." The researchers also found increasing the size of graphic health warnings reduced the appeal of packs, but not as much as plain packaging did
Similar to the colorectal cancer ,as discussed here in this article
More specifically, the British National Formulary marks with bullet points potentially harmful drug pairs which should be prescribed cautiously, under appropriate monitoring, or avoided altogether (British National Formulary, 2015)
