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Similar facial changes occur after bariatric surgery, extreme dieting and illness

This has been reflected in the medical literature

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[14] In dermal fibroblast culture and in rat wound-chamber models, GHK-Cu has been reported to modulate glycosaminoglycan and small-proteoglycan synthesis increasing chondroitin sulphate and dermatan sulphate accumulation, raising decorin mRNA and lowering biglycan mRNA i.e