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Instead, they are caused by rapid, significant weight loss

GIP receptor signaling increases cAMP levels in the brain, which activates PKA and EPAC [102]

Persistent lumps may indicate lipohypertrophy give that site a long break and report unusual changes to a clinician

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Most providers recommend baseline bloodwork before starting treatment, followed by periodic checks every 3-6 months

Likewise, side effects from this drug are more specific to the muscles, including spasms, but its ability to increase lean mass at the expense of fat suggests that it may find use in combination with other drugs to ensure body weight loss is preferentially targeted towards fat, while ensuring muscle is spared