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In retrospect, the suspicion that GLP-1RAs provoke acute pancreatitis can be traced to the diagnostic criteria used for acute pancreatitis (two out of the following three features: severe upper abdominal pain radiating into the back, elevations in amylase and/or lipase, and typical results of imaging procedures) and that GLP-1RA therapy induces abdominal symptoms in a large number of patients, as well as elevations in amylase and/or lipase

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