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60 mm = 6 cm Diameter approx
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In 2009, Cohen et al., also reported on the exposure of epithelia cell cultures to the particulate phase of cigarette smoke reducing cilliary beat increase when stimulated.13 Besides in vitro evidence, the exposure to cigarette smoke also harms mucociliary transport in humans, both in acute exposure14 as well as in its chronic counterpart.15,16 Cigarette smoking is also associated with profound changes in mucous production mechanisms
The increase of endothelial permeability will increase the probability of immune cells such as monocytes and neutrophils to infiltrate the respiratory tract, further expanding the immune response and aggravating respiratory inflammation [62]
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