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et al., Spike timing-dependent plasticity and memory, *Current Opinion in Neurobiology*, 2023, Chen, L., Li, X., Tija, M., & Thapliyal, S., Homeostatic plasticity and excitation-inhibition balance: The good, the bad, and the ugly, *Current Opinion in Neurobiology*, 2022, International Journal of Nanotechnology

Clinical Eligibility Criteria and Medical Assessment Framework Non-diabetic eligibility for GLP-1 therapy typically requires a BMI of 30 or higher, or 27 or higher with weight-related conditions like hypertension or dyslipidemia

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Median time to failure: only 11.5 months