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Most nicotine lozenge programs recommend use for 8-12 weeks, starting with frequent dosing in the first 6 weeks (one every 1-2 hours), then gradually reducing over the next 4-6 weeks (one every 2-4 hours, then 4-8 hours)

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Nicotine pouches circumvent exposure to these potential toxins via synthetic nicotine, improving safety profiles closer to nicotine gums