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CSF levels of neopterin and biopterin have been found decreased in PD patients by several groups, especially in those with early-onset PD (Fujishiro et al., 1990

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It has been therefore postulated that peroxisomes loaded with PEN2 and respective indolic GSL catabolism product move to the site of fungal entry and localization of PEN3/PDR8

the apparent lack of activity of tamoxifen plus verapamil is due to the fact that the analysis of variance considers the entire panel of results embracing patients that improve, patients that remain stable and patients in whom the disease progresses

In an early exploratory study, a significant reduction in salivary flow rate and an increase in AChE activity were observed in PD patients compared to controls, with a clear positive correlation with H&Y staging