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The choice of alternative treatment depends on the patient's overall clinical profile, including glycaemic control, cardiovascular risk, renal function, and treatment goals, in line with NICE guideline NG28 (Type 2 diabetes in adults: management)

doi: 10.1016/j.sder.2009.06.003 57 TerushkinVScopeAHalpernACMarghoobAA

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This further substantiates the potential of therapies targeting the PYY system in the treatment of obesity

KPV works to reduce inflammation and regulate immune overactivity inside the intestinal lining