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Glutathione is fragile in the gut, so swallowing a capsule means a lot of it is broken down before it ever reaches your blood

4a and Supplementary Fig

Kanias, T

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Besides being a potential source of more reactive free radicals via Fenton reaction, physiological generation of H 2 O 2 fulfills a second messenger role and can be transported across membranes by aquaporins, a family of proteins that act as peroxiporins (Sies, 2014)