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Impact of NAD+ metabolism on ovarian aging

May be considered in challenging situations (e.g., renal dysfunction, pregnancy, drug interactions, possible nonadherence)

This is a commonly referenced study from 1963 claiming a half-life of 5-6 days: nature.com/articles/198200a0 Although I would not cite it as an authority, the six-day half-life has also made it onto the B12 page in Wikipedia, seemingly unchallenged

(31980292) Imipenem is less effective in reducing valproate metabolism, so it may not be helpful

Elbers, L

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