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Some regions restrict smaller pack sizes specifically to prevent cheaper entry points into smoking pushing manufacturers toward larger standard packs

Assessments of exposures are further complicated by the multiplicity of environments where exposures take place and the difficulty of characterizing the exposure in some locations, such as public places or workplaces

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Various isoforms, namely phospholipase A2-II and A2-IV, are elevated during human AP and may affect both local disease severity and systemic complications (43)

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