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E-cigarettes and cigarettes worsen peripheral and central hemodynamics as well as arterial stiffness: A randomized, double-blinded pilot study

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[14] as noted above did not find EC use to be significantly associated with prevalence of functionally important respiratory symptoms (as noted in the section above), they did find exclusive EC use to be associated with worsening of functionally important respiratory symptoms in some analyses, though it depended on the exact cutoff used to denote functionally-important (i.e., 2 vs 3 on a 9-point scale) [14]