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Activated JNK phosphorylates numerous cytoplasmic substrates, including cytoskeletal proteins and mitochondrial proteins like Bcl-2 and Bcl-xl, in addition to controlling a few transcription factors, including c-Jun, c-Fos, ATF-2, AP-1, p53, and Elk

BMI (Body Mass Index) : A number based on height and weight used to estimate body size

Telomerase is the enzyme that maintains telomeres the protective caps at the ends of chromosomes that shorten as cells divide

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Additionally, altered DSIP responses in major depression and suicidal patients suggest its role in addressing dysregulated stress in mood disorders (5)

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