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NNMTi is a potent inhibitor of nicotinamide N-methyltransferase (NNMT) (IC50=1.2M) and can selectively bind to NNMT substrate binding site residues

(3) When the researchers running the study measured the release of fatty acids and glycerol from radiolabeled triglycerides, they observed about a 4050% increase compared to the starting levels

[DOI] [PMC free article] [PubMed] [Google Scholar] 108.Reitsma S, Slaaf DW, Vink H, et al

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