Extracellular release of galectin-8 was NDP52-dependent Galectin-8 binding to damaged vesicles triggers the recruitment of NDP52, which in turn interacts with LC3 via a non-canonical ATG8/LC3-interacting region (LIR) motif, leading to autophagy-mediated clearance of the damaged vesicles 15,25
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There were also other influential factors, such as in most of the Jeff Healey Band records, where individual band members had their own agendas and points of view that they wanted to get across as well so, quite often, Jeff would defer to other people
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