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The effect of first-pass hepatic elimination on bioavailability is expressed as the extraction ratio (ER): where Q is hepatic blood flow, normally about 90 L/h in a person weighing 70 kg.The systemic bioavailability of the drug (F) can be predicted from the extent of absorption (f ) and the extraction ratio (ER): A drug such as morphine is almost completely absorbed (f = 1), so that loss in the gut is negligible

These phospholipids are the same material that makes up your own cell membranes

When proteins are applied to the gel, they migrate through the gel and accumulate at the point along the pH gradient that corresponds to pI of the protein

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Its copper-binding properties make it a useful compound for studying tissue remodeling and extracellular matrix dynamics in controlled research environments

Integrins and other cell adhesion molecules