In contrast, peripherally acting anti-tussives exert their effects by targeting peripheral sensory nerve afferents, and could potentially provide a better approach than centrally acting therapies
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It causes an immediate effect on respiration, increasing the airways resistance and reducing the amount of oxygen absorbed into the blood
The main one is that the chemicals (PM2.5, VOCs like phenanthrene, nitrogen species, heavy metals, carbon monoxide) can be breathed in and our immune system is activated since it sees these particles as foreign and that causes inflammation and could lead to asthma and activation of clotting cascades that could lead to heart attacks or strokes
Thats the guy who was getting it done for us