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A lack of B12 can also lead to damage of the myelin sheath which wraps around our nerves so deficiency is frequently associated with neurological problems

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This further indicates that maintenance of NAD + /NADH redox balance is required for optimal energy production

The BBB can resist leakage during systemic inflammation, especially at low levels, which is partly attributed to its robust efflux system, which plays a crucial role in maintaining the brains protected environment [109, 110]