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doi: 10.3389/fpubh.2021.682355 24

We have metalloproteinases which destroy our collagen cells, then we have tissue inhibitors of metalloproteinases (TIMPs), another enzyme which will counteract the effects of the MMPs. Impaired collagen production and skin repair Because smoking causes hyperexpression of the MMPs, it leads to an imbalance between the degradation and production of collagen cells in our skin, she states