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The nicotine degrading genes are nicotine oxidoreductase ( nicA2 : BBa_K2569036), pseudooxynicotine amine oxidase ( pnao : K2768006 ), 3-succinoylsemialdehyde-pyridne dehydrogenase ( sapd ), 3-succinoylpyridine monooxygenase ( spmABC ), and 6-hydroxy-3-succinoylpyridine hydroxylase ( hspB )

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Among individuals with primary education or no diploma, smoking prevalence is projected to decrease from 26.5% (95%CI: 21.232.4%) in 1997 to 15.5% (95%CI: 10.0-23.9%) in 2025, and further to 10.7% (95% CI: 5.221.7%) by 2040

In the Midwest, the highest earning and least educated demographics were among those with the lowest quit attempt prevalence