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PMI heat-not-burn product users who have completely quit cigarettes and for whom PMI tobacco sticks represent at least 70% of their past 7-day heated tobacco consumption

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The integrated smoking system gives researchers a better understanding of smoke-related pathological changes in individual smokers, and could facilitate the discovery of more accurate biomarkers and new therapeutic targets

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Cigarette smoke contains nicotine, a substance that is highly addictive and can cause changes in the brain

Roll with machines or by hand How you roll your smokes is up to you