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The estimated relative risk incorporating between-study heterogeneity is 1.46 (95% uncertainty interval (UI) = 1.111.93

The most common adverse event associated with CHANTIX treatment is nausea, occurring in 30% of patients treated at the recommended dose, compared with 10% in patients taking a comparable placebo regimen [see Warnings and Precautions (5.9)]

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This would be new revenue to these funds.) As shown in Figure 4, the revenues would be allocated as follows: Step One