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doi: 10.3389/fmolb.2021.799294

The pathophysiological pathways involved in GH suppression in obesity are not well established, and experimental data on central effects via hypothalamic GHRH, ghrelin, and somatostatin are conflicting (20)

Obesity 21 , 23312341 (2013) S.D

while AT 2 expression was lower in rats that experienced chronic hypoperfusion as compared with controls

A recent meta-analysis of data from seven double-blind randomized controlled trials with tirzepatide lasting at least 26 weeks confirmed the cardiovascular safety of tirzepatide in patients with T2D (77)

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