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Drugs including Erastin and sorafenib, which induce ferroptosis by inhibiting the system x c , are promising anticancer therapeutics [13, 14]

In the brain of patients with mild cognitive impairment (MCI) and those with AD, the level of markers of oxidative damage to DNA, proteins, and lipids is increased, while the expression and activities of glutathione and antioxidant enzymes are reduced (reviewed in 102)

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For instance, Sun et al