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A meta-analysis of eighty-five studies 14 revealed that smoking is associated with a nearly two-fold increased risk of depression relative to never smokers and former smokers, with the association supposedly stronger in women than in men

Statistical analysis Data were weighted according to national demographic benchmarks for age, race and ethnicity, and sex

A: Not necessarily

Refills are about the same price as cigarettes, which makes sense because the company has already agreed that IQOS HeatSticks fit the American legal definition of cigarettes, and can be taxed as cigarettes

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[12] While they remain the most commonly used tobacco product among youth, rates of youth e-cigarette use have largely been on the decline since then