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PDR5 and SNQ2, are known to represent functional and structural homologues of mammalian MDR1 and MRP transporter (Zaman et al., 1994)

Cardiometabolic Disorders Cardiometabolic disorders are a collection of interrelated conditions, mainly dyslipidemia, insulin resistance, impaired glucose tolerance, hypertension, and central adiposity (Zhang et al., 2011

Misuse or off-label prescribing has led to a growing number of patients experiencing severe complications

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These are seven transmembrane-spanning proteins belonging to the G-protein-coupled receptor (GPCR) superfamily, by the cytosolic enzyme quinone reductase (QR2) [7] [Figure 2]