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[8] Meta-analysis noted in 2024 that global chewing-tobacco prevalence has increased since 1990 and that use appears particularly common among ages 1519 in many countries
A quartet of doctors from Dartmouth and Harvard weighed in on the subject of cigarette smoking in 1889
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[2] Using chewing tobacco can cause various harmful effects such as dental disease, oral cancer, oesophagus cancer, and pancreas cancer, coronary heart disease, as well as negative reproductive effects including stillbirth, premature birth and low birth weight
"Smokeless Tobacco Product Use in the United States"
The effects of tobacco have been a topic of discussion among physicians since 1888 when Doctor Robert Koch, the leading authority on infectious diseases at the time, argued that the spitting of chewing tobacco was leading to a spread of tuberculosis
