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TRPA1 is largely expressed by a subset of TRPV1-expressing neurons, and both are activated by tussive agents, so it could be possible that these two channels act in concert to elicit functional responses

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It includes the 8-item Minnesota Nicotine Withdrawal Scale (Hughes Reference Hughes2007a), which is referred to as a mood and experiences scale because smokers might be confused by completing a withdrawal scale prior to cessation and sometimes, post-cessation, may not report a symptom if they do not believe that it is due to withdrawal

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