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The drawback is the risk of overuse

[3] In the mid-1980s, Newport began an advertising campaign that targeted African Americans in urban areas

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We did not estimate RRs separately for different locations, sexes (although the RR of prostate cancer was estimated only for males and of cervical and breast cancer only for females) or age groups (although this analysis was applied to disease endpoints in adults aged 30 years only and, as detailed below, age-specific estimates were produced for the five CVD outcomes)

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