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Here is where, in theory, I should say: The problem with smoking is that it is obviously addictive

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This can then progress to abnormal nervous system signs such as excitement, twitching, hyperesthesia (increased sensitivity to light, sound, and touch), tremors, hallucinations, and seizures

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In trying to protect your mind from the neuro-chemical influence of the toxic natural pesticide nicotine, in some brain regions it actually desensitized important neuro-chemical circuits by reducing neurotransmitter receptor sites (down-regulation), in other regions by increasing the number of receptors (up-regulation), and still others by diminishing the number of transporters