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Lancet Diabetes Endocrinol 2021;9:65362.ArticlePubMed 75

Most discomfort resolves entirely with three changes: room-temperature equilibration before drawing, slower plunger depression during injection, and rotating injection sites to prevent localized tissue fatigue

Acknowledgments We would like to thank Lisha Zhao for her contribution to the writing and revision of this article

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While injection at home may be daunting for some, the needles involved in peptide therapy tend to be extremely small and thin, making the process almost painless compared to other types of injections

Garcia-Lopez, M., et al