249,445,446,447,448,449 Uric acid exerts multifaceted effects on endothelial function and vascular health through its interactions with NO, ROS, and inflammatory pathways, highlighting its potential role in the pathogenesis of cardiovascular diseases like atherosclerosis
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On the one hand, the necessity of conducting epidemiological studies which are specific to the socio-economic, linguistic, and legal context of a country, and even more the need for figures to be comparable over time (meaning the ability to follow up and therefore a preference for studies already underway at a national level), reduces the validity of such comparisons
Circulation 2005