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By 2018, roughly one out of five high schoolers (20.8%) had used an e-cigarette in the last 30 days

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These cravings are often overwhelming and difficult to ignore, usually leading individuals to relapse if not effectively managed

Regardless of what method of taking the substance, it reacts with the same pleasure and reward receptors in the brain as other stimulants such as cocaine or amphetamines, though on a smaller scale