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The extremely high concentration of nicotine in e-cigarettes has significant mal-effects on oral health that should not be ignored. Cancer: Similar to traditional cigarettes, e-cigs can potentially lead to cancer, says Dr

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Moreover, POU2F3 KO cultures exhibited strong depletion in the number of likely ionocytes (FOXI1 + ) and PNECs ( GRP + ) as assessed by wholemount IF or FISH microscopy, respectively (Fig