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A total of 230,000 households in the UK live in smoking-induced poverty and the children of smokers are 3 times as likely to start to smoke, perpetuating the cycle of disadvantage (Nyakutsikwa and others, 2022

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A challenge of observational studies is potential confounding, because without randomization, certain factors (confounders) may be systematically and unequally distributed across e-cigarette users and non-users

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