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Semaglutide affects your digestive system, and starting the medication with optimal hydration can significantly reduce the likelihood of early side effects like headaches or mild nausea

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Tirzepatide (Mounjaro, Zepbound): Plateaus tend to arrive later, at 9 to 15 months, with average total weight loss of 20 to 25 percent

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These agonists not only enhance GLP-1 release but also suppress the expression of pro-inflammatory cytokines, including IL-2, IL-17a, interferon-, and TNF- (Yusta et al., 2015)

Among them, the constant feeling of fullness reduces appetite and potential intake of vital nutrients