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A spokesman told CNBC in September that "history has shown prohibition does not work" and "education and those measures should be pursued before government starts considering the prohibition and ban of legal products." San Francisco estimates the ban would result in a decrease of $50 million per year in flavored cigarette sales

A long-term exposure study of IQOS (12 weeks) reported 20 times less toxicity on human bronchial epithelial cells regarding oxidative stress, DNA damage, and epithelial-to-mesenchymal transition (a marker of carcinogenesis) 61

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To explore the etiology of the higher mortality rate in UC smokers than in nonsmokers, we have conducted a subgroup analysis based on the cause of death

3: The number of times Cal struck out without his focus