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It ranges from 0 to 100, 0 meaning a very common coin or banknote and 100 meaning a rare coin or banknote among Numista members

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In particular, overexpression of SESN1 or SESN2 has been reported to induce the autophagic degradation of Keap1 and increase the activity of Nrf2 ( Mutual regulation of autophagy and oxidative stress Under oxidative stress, autophagy is activated to protect cells from apoptosis (Mizushima, 2009), whereas, inhibition of autophagy leads to accumulation of oxidative stress damage and cell death (Lee et al., 2012)

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