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When UA was applied at concentrations of 200 M and 400 M, cell viability did not change significantly

Yuan H, Perry CN, Huang C, Iwai-Kanai E, Carreira RS, Glembotski CC et al

As an example, findings from a phase I clinical study on nabulizumab, an anti-PD-1 antibody for solid tumor treatment, indicated survival rates of 22.4 and 16.8 months for non-small cell lung cancer and renal cell carcinoma, respectively [115]

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The Shc adaptor protein is critical for VEGF induction by Met/HGF and ErbB2 receptors and for early onset of tumor angiogenesis

We tested whether COP1 or DDD-COP1 directly interacts with p53 using co-expression and pull-down assays in human cells, and found no detectable interaction under the conditions tested (Supplementary Fig