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The detection of SBS4 (a hallmark of tobacco-induced mutagenesis) in the organoid model indicates that chronic WCSE exposure can elicit molecular alterations resembling those found in smoker-derived tumors, effectively bridging in vitro oxidative adaptation with in vivo mutational landscapes

Or applying expensive ointment to a cold sore, even after learning the ointment was making it worse

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Acute gonorrhea typically presents with symptoms such as painful urination and pus discharge