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doi:10.1002/14651858.CD009670.pub2

Nicotine causes acute vasoconstriction with each use, which can temporarily impair blood flow immediately after vaping

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Figure 2 compares reported proportions of ever use of e-cigarettes in teenagers across high-income countries, including Canada, the United States, Great Britain, and Europe between 20152017 and 20182019 25,26,27,28

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"We've been forced into a position where they're going to be taking our property, so we will bring a legal challenge," Jerome Abelman, head of corporate and regulatory affairs for British American Tobacco, told Reuters.