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Such studies should confirm that cigarette smoke exposure causes lung inflammation (positive control), while cMRTP aerosols should have a very limited effect on this mechanism [41]

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This is not surprising, as COPD and lung cancer share several underlying disease mechanisms, such as oxidative stress and inflammation [59]

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Further, if more tobacco consumers are going into c-stores, this bodes well for c-stores' other nontobacco merchandise sales. The likelihood that CVS tobacco consumers will merely shift to the c-store channel is also good news for manufacturers, who Herzog predicts will feel no impact from CVS exit