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PGC-1, a key regulatory factor for mitochondrial biogenesis, is central in regulating mitochondrial function and cellular energy metabolism (Halling and Pilegaard, 2020)

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Nicotine constricts blood vessels and reduces the flow of oxygen and nutrients essential for wound healing

[4] In addition, children exposed to e-cigarettes were more than 5 times more likely to be admitted to the hospital and more than twice as likely to have a severe health outcome than kids exposed to regular cigarettes

The three possibilities are in Table 4.3