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While higher cotinine levels were not associated with significant differences in scores that measured memory and language fluency, they were associated with significantly worse scores on the Digit Symbol Substitution Test (DSST), a test that reflects multiple aspects of cognition, such as processing speed, attention, and working memory

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By supplementing with creatine, individuals are essentially increasing their body's natural stores of this compound, which can help improve strength, endurance, and muscle recovery

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