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Acsl4 fl/fl mice were obtained from Cyagen Biosciences (Jiangsu), and Fsp1 fl/fl mice and Ksp Cre-ERT2 mice were sourced from GemPharmatech (Jiangsu)

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Abstract Nephrolithiasis is a prevalent urological disorder in which calcium oxalate (CaOx) stones are most common, and accumulating evidence suggests that oxidative stress and ferroptosis contribute to CaOx-induced tubular epithelial injury